Jakub Rychter, PhD

Description

Freelance medical translator specializing in German and Dutch to English translations. Leveraging expertise in medicine and life sciences alongside advanced language skills and cultural insights developed through an international upbringing.
Profile:
- Ph.D. in Physiology and Immunology
- Bilingual in English and Dutch, developed through upbringing in the Netherlands.
- Near-native proficiency in German, acquired growing up in Germany
- Over eight years of work experience in biomedical research in academia
- Experience in writing, editing, reviewing, and publishing medical research publications
- Author of several research publications in major international journals in the fields of surgery, gastroenterology, parasitology, and physiology



Work Experience:
- Freelance medical translator since 2011
- Guest professor, Pompeu Fabra University, Spain
- Dissertation supervisor at Autonomous University of Barcelona, Barcelona, Spain (link)
- Postdoctoral researcher, Autonomous University of Barcelona, Barcelona, Spain
- Ph.D. candidate, Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, the Netherlands
- Quality Assurance Coordinator, Department of Pharmaceutical Affairs, Sandoz/Novartis Group, Almere, the Netherlands


Education:
- Ph.D. in Physiology and Immunology, Utrecht University, the Netherlands
- M.Sc. in Medical Biology, Radboud University, the Netherlands
- B.Sc. in Medical Biology, Radboud University, the Netherlands


Publications:


Mast cell degranulation inhibits motor patterns of human ileum and sigmoid colon in vitro: relevance for postoperative ileus. Rychter J, Ortega O, Berdun S, Arenas C, Lopez I, Espin F, Vergara P, Clavé P. Neurogastroenterol Motil. 2015 May 13. doi: 10.1111/nmo.12589. [Epub ahead of print]


Colonic smooth muscle cells and colonic motility patterns as a target for irritable bowel syndrome therapy: mechanisms of action of otilonium bromide. J Rychter, F Espin, D Gallego, P Vergara, M Jime©nez, P Clav√©. Therap Adv Gastroenterol 7(4):156-66(2014)



Intestinal inflammation in postoperative ileus: pathogenesis and therapeutic targets. J Rychter, P Clavé. Gut 62(11):1534-5(2013)


CGRP1 receptor activation induces piecemeal release of protease-1 from mouse bone marrow-derived mucosal mast cells
J Rychter, L van Nassauw, J-P Timmermans, LMA Akkermans, RHS Westerink, ABA Kroese. Neurogastroenterology and Motility 23(2):57-68(2011)



Impairment of intestinal barrier and secretory function as well as egg excretion during intestinal schistosomiasis occur independently of mouse mast cell protease-1. J Rychter, L. van Nassauw, JK Brown, E van Marck, PA Knight, HRP Miller, ABA Kroese, J-P Timmermans. Parasite Immunology 32:221-31(2010)


Pretreatment but not treatment with probiotics abolishes mouse intestinal barrier dysfunction in acute pancreatitis.
J Rychter, L van Minnen, A Verheem, H Timmerman, G Rijkers, M Schipper, H Gooszen, L Akkermans, ABA Kroese. Surgery 145:157-67(2009)


On the contribution of mucosal mast cells to the regulation of mouse intestinal barrier function. J Rychter, Doctoral thesis (2010).


Co-authored publications:


Effects of nerve growth factor antagonist K252a on peritoneal mast cell degranulation.
Berdun S, Rychter J, Vergara P. Am J Physiol Gastrointest Liver Physiol. 2015 Nov 15;309(10):G801-6.


Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery.
Berdun S, Bombuy E, Estrada O, Mans E, Rychter J, Clavé P, Vergara P. Neurogastroenterol Motil. 2015 Jun;27(6):764-74.


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